Smoking Reduction Intervention for Smokers Not Willing to Quit Smoking: a Randomised Control Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00563329

Enrollment

3826

Registered

2007-11-26

Start date

2004-10-31

Completion date

2006-07-31

Last updated

2013-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking Cessation

Keywords

Smokers who are not willing to quit in the near future but intend to reduce smoking

Brief summary

The aims of this study are (1) to examine the effect of smoking reduction intervention (reduction counseling and nicotine replacement therapy, NRT) (a) on smoking cessation and (b) on reducing daily cigarette consumption among smokers not willing to quit smoking but want to reduce smoking, and (2) to examine the effect of adherence intervention in producing a higher (a) adherence rate, (b) reduction rate, and (c) quit rate.

Interventions

PROCEDUREReduction Intervention + Adherence Intervention

BEHAVIORALReduction Intervention

PROCEDUREcontrol

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

SINGLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Age 18 or above * Ethnic Chinese male or female * Smokes at least 2 cigarettes per day * Have no intention to quit in the near future * Intends to reduce smoking in the next 7 days * Has no contraindication to NRT

Exclusion criteria

* Subjects who are psychologically or physically unable to communicate * Children and teenagers (age below 18) * Pregnant or intention to become pregnant within the next 6 months * Those on regular psychotropic medications and in the presence of any serious health problems that may make them unsuitable for using NRT, such as recent stroke, palpitation, or other life threatening conditions

Design outcomes

Primary

Measure	Time frame
quit rate	6 months
Reduction Rate (reduction of cigarette consumption by at least 50% compared with baseline)	6 months
Adherence Rate to NRT	4 weeks

Secondary

Measure	Time frame
Validated quit rate (by measuring exhaled CO and urinary cotinine level)	6 months
Quit rate without validation	1 month
self-reported use of NRT for at least 4 weeks or 8 weeks, without cotinine validation	1 month / 3 month

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026