Osteoarthritis of the Knee
Conditions
Brief summary
The purpose of this study is to discover whether arthroscopic surgery is helpful in controlling the symptoms of osteoarthritis of the knee.
Detailed description
Although arthroscopic surgery has been widely used for osteoarthritis of the knee, scientific evidence to support its efficacy is lacking. This study will compare optimized physical and medical therapy alone with arthroscopic treatment in addition to optimized physical and medical therapy.
Interventions
PROCEDUREArthroscopic surgery
Arthroscopic surgery to treat unresolved symptoms of osteoarthritis of the knee
OTHERPhysical and medical therapy
Treatment with physical and medical therapy alone
Sponsors
Canadian Institutes of Health Research (CIHR)
University of Western Ontario, Canada
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Idiopathic or secondary osteoarthritis of the knee with Grade II to IV radiographic severity as defined by the modified Kellgren and Lawrence classification
Exclusion criteria
* Patients with inflammatory or post-infectious arthritis * Those who had undergone previous arthroscopic treatment for knee osteoarthritis * Those with isolate Grade III to IV medical compartment osteoarthritis with greater than 5 degrees of varus deformity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Function, pain and quality of life based on the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Health utility using the Standard Gamble Technique | 24 months |
Countries
Canada
Outcome results
None listed