Study of Vanadium Supplement in Patients With Impaired Glucose Tolerance

Effect of Vanadium on Insulin Sensitivity in Patients With Impaired Glucose Tolerance

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00561132

Enrollment

Registered

2007-11-20

Start date

2003-11-30

Completion date

2004-11-30

Last updated

2007-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prediabetic State

Keywords

vanadium, insulin sensitivity, impaired glucose tolerance, triglycerides

Brief summary

The purpose of this study was to evaluate if the vanadium can improve the insulin sensitivity in patients with impaired glucose tolerance. Secondary purpose of this study was to assess changes on metabolic profile, weight and blood pressure.

Interventions

DIETARY_SUPPLEMENTVanadyl sulfate

50 mg twice daily orally for a period of 4 weeks

OTHERMagnesium oxide

Validation of similar appearance and weight to the intervention component orally 1 unit (\<50 mg) twice daily for a period of 4 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

40 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Diagnosis of impaired glucose tolerance * Body mass index from 25 to 35 kg/m2 * History of type 2 diabetes mellitus in the first branch

Exclusion criteria

* Taking medication with known effects on carbohydrate or insulin metabolism * Thyroid diseases * Hepatic diseases

Design outcomes

Primary

Measure	Time frame
Changes on insulin sensitivity assessed with a euglycemic-hyperinsulinemic clamp technique	4 weeks

Secondary

Measure	Time frame
Changes on metabolic profile	4 weeks
Changes on anthropometrical measures	4 weeks

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026