PTSD, Schizophrenia
Conditions
Keywords
Schizophrenia, PTSD, Cognition
Brief summary
We propose to establish a database characterizing the presence or absence of comorbid PTSD in veterans with schizophrenia or schizoaffective disorder (SAD) receiving services at the Durham VA Medical Center. In addition to the evaluation of PTSD symptoms in veterans with schizophrenia or SAD, this database will facilitate the investigation of a number of additional specific research questions relevant to veterans with psychotic disorders.
Detailed description
See brief summary
Interventions
None listed
Sponsors
Durham VA Medical Center
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 72 Years
Healthy volunteers
No
Inclusion criteria
1. 18-72 years of age, any ethnic group, either sex. 2. Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) diagnosis of schizophrenia or schizoaffective disorder. 3. Ability to fully participate in the informed consent process, or have a legal guardian able to participate in the informed consent process.
Exclusion criteria
1. Unstable current medical or neurological illness. 2. Significant suicidal or homicidal ideation. 3. Pregnant women or women who could be pregnant.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Brief Assessment of Cognition in Schizophrenia (BACS) | Visit 1 | The Brief Assessment of Cognition in Schizophrenia (BACS) includes brief assessments of executive functions, verbal fluency, attention, verbal memory, working memory and motor speed. Z-scores are calculated from composite scores. Higher z-scores are indicative of better cognitive performance, lower z-scores are indicative of lower cognitive performance. Range of z-scores anticipated to be between -3 and 3. |
Countries
United States
Outcome results
None listed