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Effects of Fetal, Infant, and Early Childhood Exposures on Adult Cancer Risk in Women

Fetal, Infant and Early Childhood Antecedents of Cancer in Women: Maternal Cohort Study of the Nurses' Health Studies

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00559039
Enrollment
128700
Registered
2007-11-16
Start date
2000-10-31
Completion date
2006-10-31
Last updated
2012-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Unspecified Adult Solid Tumor, Protocol Specific

Keywords

breast cancer, unspecified adult solid tumor, protocol specific

Brief summary

RATIONALE: Gathering information about pregnancy, infancy, and early childhood exposures may help doctors identify cancer risk factors, and may help the study of cancer. PURPOSE: This natural history study is looking at the effects of fetal, infant, and early childhood exposures on adult cancer risk in women.

Detailed description

OBJECTIVES: * Determine if fetal, infant, and early childhood exposures are associated with adult cancer risk in women. OUTLINE: Mothers of nurses complete questionnaires to collect maternal data, such as pregnancy weight gain, diet during pregnancy, maternal pre-eclampsia, gestational diabetes, gestational age at birth, birth weight, and infant feeding practices. Maternal data is linked to other data collected from critical time periods in the nurses's life cycle, such as menarche, first pregnancy, or adult dietary intake.

Interventions

OTHERquestionnaire administration
PROCEDUREevaluation of cancer risk factors

Sponsors

National Cancer Institute (NCI)
CollaboratorNIH
National Institutes of Health Clinical Center (CC)
Lead SponsorNIH

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 89 Years
Healthy volunteers
Yes

Inclusion criteria

DISEASE CHARACTERISTICS: * Mother of a nurse who is a participant in the Nurses' Health Studies I and II * Nurse free of cancer in the year 2000 PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Design outcomes

Primary

MeasureTime frame
Diagnosis of incident cancers and other chronic diseases
Mortality

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026