Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)

Salivary Catecholamines in Aphthous Stomatitis

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00556686

Enrollment

Registered

2007-11-12

Start date

2006-08-31

Completion date

2009-12-31

Last updated

2015-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Canker Sore

Brief summary

The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.

Detailed description

The purpose of this study is to determine if salivary catecholamines are elevated in patients with the disease aphthous stomatitis. The results of this study will be combined with those performed in collaboration with a co-Investigator to understand the effects of catecholamines on mucosal wound healing and oral epithelial cell migration.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age 18 or older, both genders * History of recurrent aphthous ulcers with 4 or more episodes per year

Exclusion criteria

* History of salivary gland disease including Sjogren's disease, parotitis, and sialolithiasis * History of benign or malignant salivary gland tumor * History of celiac disease, ulcerative colitis or Crohn's disease * Patients on medications that affect salivary flow such as anti-depressants and anti-cholinergic medications

Outcome results