Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00556036

Enrollment

Registered

2007-11-09

Start date

2006-03-31

Completion date

2009-03-31

Last updated

2020-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity

Keywords

healthy, overweight, obese, anorexia nervosa, weight, cortisol, hormone, bone density, bone, osteopenia, osteoporosis, amenorrhea, menses, irregular, stress, depression, exercise, diet

Brief summary

The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Amenorrhea for at least three months (unless participating as healthy control) * Normal TSH or free thyroxine (free T4).

Exclusion criteria

* A condition known to affect bone metabolism, including Cushing's syndrome or renal failure, with the exception of bone fracture. * Any medication known to affect bone metabolism within 3 months of the study, including estrogen and progestins. Patients receiving depot medroxyprogesterone (Depo-Provera) will be excluded from participating for 6 months after their last injection. * Pregnant and/or breastfeeding. * Diabetes mellitus. * Active substance abuse, including alcohol.

Countries

United States

Outcome results