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PERG and mfPERG in Band Atrophy

Pattern Electroretinogram and Multifocal Pattern Electroretinogram For the Detection of Neural Loss in Patients With Permanent Temporal Visual Field Defect From Chiasmal Compression

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00553761
Enrollment
30
Registered
2007-11-06
Start date
2006-08-31
Completion date
2009-07-31
Last updated
2011-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Band Atrophy

Keywords

Band atrophy, Pattern electroretinogram, Chiasmal compression, Neural loss, Electrophysiological tests

Brief summary

The study is designed to evaluate the ability of pattern electroretinogram (PERG) and multifocal pattern electroretinogram (mfPERG) to measure and identify the pattern of band atrophy of the optic nerve in patients with long standing chiasmal lesions. The hypothesis is that these electrophysiological tests were able to identify this such pattern. The idea is to investigate the ability of the these electrophysiological technics in detecting the neural loss from chiasmal compression and to evaluate the ability of PERG and mfPERG parameters to differentiate between eyes with band atrophy of the optic nerve and healthy eyes.

Interventions

Full field and hemifield (nasal and temporal) stimulation transient pattern electroretinogram (PERG) were recorded both in patients and controls.

Sponsors

Fundação de Amparo à Pesquisa do Estado de São Paulo
CollaboratorOTHER_GOV
University of Sao Paulo
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

1. Visual acuity better than 20/30 2. Refractive error less 5 spherical diopter and 3 cylinder diopter 3. Temporal field defect

Exclusion criteria

1. Presence of glaucoma and optic nerve anomalies 2. Anormal nasal field

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 3, 2026