End Stage Liver Disease
Conditions
Brief summary
Severe hypotension during reperfusion in liver transplantation is a frequent adverse event. Rare data exist so far about pathophysiology of this phenomenon. The exact role of left ventricular function, which might be impaired causing hypotension, has not been elucidated during the period of reperfusion. Goal of this study is to: * perform transesophageal echocardiography in order to assess systolic and diastolic left ventricular function during reperfusion * determine inflammatory mediators in the plasma which could cause left ventricular dysfunction
Interventions
BEHAVIORALTransoesophageal echocardiography
Transoesophageal echocardiography in liver transplantation: left ventricular function during reperfusion
Sponsors
University of Zurich
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Patients on waiting list for liver transplantation. * Age: 18-75 years.
Exclusion criteria
* Strictures, tumours and diverticula of the oesophagus. * History of oesophageal varices with recent bleeding. * Oesophageal varices and prothrombin time less than 20% or platetlets les than 30000/ml. * Instable cervical spine. * Involvement in other studies.
Countries
Switzerland
Outcome results
None listed