Study to Determine a Preference Between Sildenafil or Tadalafil Treatment for Problems Getting an Erection

Switching From Sildenafil Citrate to Tadalafil in Treatment of Erectile Dysfunction: Assessment of Treatment Preference

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00547352

Enrollment

160

Registered

2007-10-22

Start date

2004-06-30

Completion date

2005-06-30

Last updated

2007-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impotence

Brief summary

To determine if men with problems getting and keeping an erection prefer treatment with tadalafil or sildenafil.

Interventions

DRUGtadalafil

20 mg tadalafil tablets taken by mouth, as needed, no more than once a day for 8 weeks.

DRUGsildenafil

Current users of sildenafil citrate for a minimum of 6 weeks prior to visit 1 will continue with an individual dosage to be taken no more than once a day for an additional 4 weeks.

Study design

Intervention model

CROSSOVER

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* History of erection problems * Anticipate a monogamous female sexual relationship * Abstain from other erection treatments throughout the study * Currently use sildenafil

Exclusion criteria

* Other primary sexual disorders * History of radical prostatectomy or other pelvic surgery that affected being able to have an erection * History of penile implant or clinically significant penile deformity. * Nitrate use * Certain heart problems

Design outcomes

Primary

Measure	Time frame
Patient choice of drug at visit 5	14-15 weeks

Secondary

Measure	Time frame
PAIRS self-administered scale scores	14-15 weeks

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026