Differential Metabolic Effects of Statins

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00546559

Enrollment

Unknown

Registered

2007-10-19

Start date

2004-01-31

Completion date

2008-03-31

Last updated

2008-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercholesterolemia

Keywords

Lipophilic statins, Insulin resistance, simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.

Brief summary

The investigators hypothesized simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.

Interventions

DRUGstatins (simvastatin, pravastatin)

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

25 Years to 75 Years

Inclusion criteria

* Low-density lipoprotein cholesterol levels \> 130

Exclusion criteria

* Overt liver disease, * Chronic renal failure * Hypothyroidism * Myopathy * Uncontrolled diabetes * Severe hypertension

Design outcomes

Primary

Measure	Time frame
Simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.	—

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026