FindTrial
Sign In

Simvastatin Reduces Adiponectin Levels and Insulin Sensitivity

Phase 4 Study of Simvastatin That Affects Insulin Sensitivity

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00546182
Enrollment
Unknown
Registered
2007-10-18
Start date
2004-01-31
Completion date
Unknown
Last updated
2007-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercholesterolemia

Keywords

Lipophilic statins, Insulin resistance, hypercholesterolemic patients

Brief summary

We hypothesized simvastatin may reduce adiponectin levels and insulin sensitivity in overweight hypercholesterolemic patients.

Interventions

None listed

Sponsors

Gachon University Gil Medical Center
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
25 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Low-density lipoprotein cholesterol levels more than 100 and body mass index more than 23.0

Exclusion criteria

* Patients with overt liver disease * Chronic renal failure * Hypothyroidism, myopathy * Uncontrolled diabetes * Severe hypertension, stroke * Acute coronary events * Coronary revascularization within the preceding 3 months, or * Alcohol abuse.

Design outcomes

Primary

MeasureTime frame
simvastatin may reduce adiponectin levels and insulin sensitivity in overweight hypercholesterolemic patients—

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026