Structured Stroke Management Improves Outcome at 6 Months

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00544622

Enrollment

Unknown

Registered

2007-10-16

Start date

2002-01-31

Completion date

2003-03-31

Last updated

2008-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

Stroke treatment, Rehabilitation, Stroke chain, Stroke unit

Brief summary

Background/Aim of the study: To further reduce the 6 months stroke morbidity and mortality in a high volume stroke hospital and to compare the results with national and international data. Methods: 204 consecutive stroke patients are analyzed in a prospective study in a single center teaching institution. The intervention consists of a structured therapeutic chain of 290 collaborating GPs, a standardised acute hospital proceeding overlapping with an early integrated neurovascular rehabilitation within the same institution. Primary endpoints include death and dependence at 6 months, secondary endpoints are the length of hospital stay (LOS) and the quantitative analysis of physical and psychosocial impairments. The data are directly compared with the same endpoints of the Swiss subgroup of the international stroke trial (IST).

Interventions

PROCEDUREstructured therapeutic chain of stroke treatment

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Inclusion criteria

* An acute cerebrovascular event (ischemic stroke or intra-cerebral bleeding (ICB)) with the signs and symptoms of an acute stroke according to the World Health Organisation definition of acute stroke14 within the last 12 hours without the need or possibility of a neurosurgical intervention * No thrombolytic therapy within the first 3 hours (in order to allow the correct comparison with the Swiss cohort of the IST trial * The informed consent of the patient or, if not possible, of the relatives * Living at home before the event * Lack of participation in another trial.

Exclusion criteria

* Thrombolytic therapy within the first 3 hours (in order to allow the correct comparison with the Swiss cohort of the IST trial * No informed consent of the patient or, if not possible, of the relatives * Not living at home before the event * Participation in another trial (26 patients were excluded because of TIA with full recovery within 24 hours after the event)

Design outcomes

Primary

Measure	Time frame
Mortality, dependence, psychoscial outcome	—
Mortality, dependence and psychosocial outcome	6 months endpoint

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026