Effect of Oxygen on Core Temperature

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00543452

Enrollment

Registered

2007-10-15

Start date

2005-02-28

Completion date

2010-09-30

Last updated

2011-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Disease, Cheyne-Stokes Respiration

Brief summary

Study of the effect of oxygen on the frequency of central apnea, sleep and body temperature in patients with a cardiac disease

Interventions

OTHEROxygen

4 liters of oxygen a minute

OTHERAir from a placebo oxygen delivery

4 liters a minute of air from a placebo device

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Cardiac disease and Cheyne-Stokes respiration and controls without Cheyne-Stokes respiration

Exclusion criteria

* Obstructive sleep apnea

Design outcomes

Primary

Measure	Time frame	Description
Core temperature	One day	This is an experitmetal study. Subjects receive oxygen or placebo-air during one night in random order. Outcome measure, i.e.core temperatue is measured continuously during this night with ongoing treatment of oxygen or placebo-air

Secondary

Measure	Time frame	Description
Sleep stages, apnea-hypopnea index	One day	This is an experitmetal study. Subjects receive oxygen or placebo-air during one night in random order. Outcome measure, i.e.the amount of differernt sleep stages, total sleep time and apnea-hypopnea index is measured during this night with ongoing treatment of oxygen or placebo-air

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026