Biochemical Marker to Predict the Recurrence of Atrial Fibrillation After Surgical Maze Procedure

Plasma ANP and NT-pro-BNP, Atrial Anatomical Change May Determine the Outcome of Maze Operation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00542659

Enrollment

Registered

2007-10-11

Start date

2005-02-28

Completion date

2008-02-29

Last updated

2011-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

Atrial fibrillation, Maze procedure

Brief summary

The role of plasma NT-proBNP, hsCRP, TIMP-1(Tissue inhibitors of MetalloProteinase-1),TGF-b, MMP-3(Matrix MetalloProteinase-3), and pro-MMP-1 in predicting the recurrence of AF after surgical Maze procedure. The association of expression of CTGF, TGF-b, BNP, ANP, collagen-1, and collagen-3 in LA with the recurrence of AF after surgical Maze procedure.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 75 Years

Healthy volunteers

Inclusion criteria

* The patients who have valvular heart disease with atrial fibrillation and are scheduled for operation

Exclusion criteria

* Coronary heart disease * Congestive heart failure

Design outcomes

Primary

Measure	Time frame
AF recurrence	year

Countries

South Korea

Outcome results