Hip Replacement Arthroplasty
Conditions
Keywords
Hip Replacement Arthroplasty, Hydroxyethyl Starch, Hemodilution, Hetastarch, Colloids
Brief summary
Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate. This research has been analyzing hemodynamic parameters and the coagulation status before and after the pre-expansion with the solutions above mentioned.
Detailed description
This trial is randomized an blind to the physician who is analyzing the results.It has been select adults; both sex; ASA I and II. These patients must be submitted to hip arthroplasty replacement. The anesthesia technique is single shot spinal anesthesia. Primary endpoint: assessment alternative; technique replacement volemic with HES 130/04. Secondary endpoint: haemostatic abnormalities; blood loss; transfusion blood.
Interventions
Dosage: 30ml/kg; frequency: one time; duration: 60min
DRUGRinger's lactate
Dosage: 30ml/kg; frequency: one time; duration: 60min.After 10ml-kg-h both groups
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients involved: adults, ASA I and II; * Surgery: hip replacement arthroplasty.
Exclusion criteria
* Allergy starch; * Anemia; * Dysfunction renal; * Heart insufficiency; * Morbid obesity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HES expansion plasmatic efficacy | 24 hours |
Secondary
| Measure | Time frame |
|---|---|
| Blood transfusion | 24 hours |
| Haemostatic alterations | 24 hours |
Countries
Brazil
Outcome results
None listed