Major Depression
Conditions
Keywords
Major depression, Primary care
Brief summary
This is a pilot study. The purpose of this study is to determine whether adding 4 months of behavioral therapy to primary care physician medication treatment(relative to medication treatment alone) improves outcomes for persistently depressed primary care patients.
Interventions
BEHAVIORALbehavior therapy
10 sessions over 4 months
DRUGMedication prescribed by PCP
Can include any antidepressant medication
Sponsors
Memorial Hospital of Rhode Island
Butler Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Current MDD or MDD within the past year or current dysthymia * PHQ-9 \> 10 * have been prescribed an antidepressant medication (by their PCP) at least 8 weeks before pre-treatment timepoint * are able to speak, read, and understand English sufficiently well to complete study procedures * are between the ages of 18 and 70
Exclusion criteria
* presence of significant suicidal ideation or risk * history of bipolar disorder, schizophrenia, psychotic symptoms, or severe alcohol or drug problems within the past year; * history of antisocial personality disorder or borderline personality disorder; * currently in psychotherapy or have received counseling more frequently than once per month in the past year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression symptoms | 4 months |
Secondary
| Measure | Time frame |
|---|---|
| Psychosocial functioning | 4 months |
Countries
United States
Outcome results
None listed