Alcohol Abuse, Schizophrenia
Conditions
Keywords
Schizophrenia, Alcohol Abuse, Bone Density
Brief summary
People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis. To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol abuse, the investigators will compare bone mineral density between patient with schizophrenia with and without alcohol abuse.
Detailed description
People with schizophrenia has been known as a high risk groups for developing osteoporosis, because of lack of exercise, poor nutrition and high rate of smoking. Those with alcohol abuse may be higher risk group than one with schizophrenia without alcohol abuse, because they frequently have several medical problems such as liver dysfunction, Vitamin D deficiency, hyperparathyroidism and those medical condition increase risk for developing osteoporosis. Also alcohol itself can increase bone loss too by disturbing bone remodeling and enhancing bone fragility. To compare the prevalence of bone mineral density in patients with schizophrenia with alcohol abuse to those without alcohol problem, we will investigate BMD in large population of Korean patients with those illnesses.
Interventions
OTHERNo Intervention
No Intervention
Sponsors
Inje University
Study design
Observational model
CASE_CONTROL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* DSM-IV diagnosis of schizophrenia * Onset of illness more than 5 years.
Exclusion criteria
* No severe Medical and endocrinological disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of bone mineral density | cross sectional and prospective |
Secondary
| Measure | Time frame |
|---|---|
| The effects of Smoking and antipsychotic drug on BMD | Cross sectional Study |
Countries
South Korea
Outcome results
None listed