Initial Versus Delayed Operation for Treatment of Complicated Appendicitis In Children

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00540189

Enrollment

Registered

2007-10-05

Start date

2008-05-31

Completion date

2010-01-31

Last updated

2016-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perforated Appendicitis

Keywords

appendicitis, perforated, children

Brief summary

To determine the most cost effective way to treat children with perforated appendicitis we will randomize all children presenting with perforated appendicitis to initial operation, with in 24 hours of admission, or to initial antibiotics, with or without percutaneous drainage, and subsequent interval appendectomy after 8 weeks. Our outcomes will include cost, complications, length of stay, and quality of life measures.

Interventions

PROCEDUREInitial appendectomy

PROCEDUREInterval appendectomy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

2 Years to 17 Years

Healthy volunteers

Inclusion criteria

children * Age 2-17 with a diagnosis of perforated appendicitis

Exclusion criteria

* Age \<2 and \>18 * Pregnancy * Immunocompromise

Design outcomes

Primary

Measure	Time frame
cost effectiveness	3 months post entry into the study

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026