Bipolar Disorder, Schizophrenia
Conditions
Brief summary
Investigation of the impact of Zeldox on metabolic parametres in patients with bipolar disorder or with schizophrenia and impact of the treatment for the quality of life
Detailed description
observational survey consecutive patient sampling
Interventions
OTHERno intervention
no intervention
Sponsors
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Manic and mixed episodes of up to moderate severity in patients with type I and II bipolar disorder and schizophrenia; either first diagnosed or repeated episodes.
Exclusion criteria
Patients with a history of hypersenzitivity to Ziprasidone. Previous insufficiency of the Ziprasidone´s treatment. The break of the previous therapeutic condition.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | Baseline | CGI-S assesses the severity of the condition at baseline using a scale that ranges from (1)Normal, not ill at all to (7) Among the most severely ill patients. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Young Mania Rating Scale (YMRS) Scores (Bipolar Population): Change From Baseline | Baseline to final visit (12 weeks) | The YMRS is an 11-item questionnaire that rates the severity of bipolar disorder, with higher score indicating greater severity of disease. Change: score at final visit minus score at baseline. |
| Montgomery Asberg Depression Rating Scale (MADRS) Scores (Bipolar Population): Change From Baseline | Baseline to final visit (12 weeks) | MADRS measures treatment effect on depression severity. MADRS assesses apparent and reported sadness, inner tension, sleep, appetite, concentration difficulties, lassitude, inability to feel, pessimistic thoughts, and suicidal thoughts. Higher score indicates greater severity of disease. Change: score at final visit minus score at baseline. |
| Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | Final visit (week 12) | CGI-C assesses change in severity of the conditionusing a scale that ranges from (1) very much improved to (7) very much worse. Higher score indicates increasing severity of disease. |
| Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | Final visit (week 12) | CGI-C assesses change in severity of the conditionusing a scale that ranges from (1) very much improved to (7) very much worse. Higher score indicates increasing severity of disease. |
| Brief Psychiatric Rating Scale (BPRS) Scores (Schizophrenia Population): Change From Baseline | Baseline to final visit (week 12) | BPRS is an 18-item scale with 11 general symptom items, 5 positive-symptom items, and 2 negative symptom items. The physician completes the BPRS, and each item is scored on a 7-point scale, with higher score indicating greater severity of symptom. Change: score at final visit minus score at baseline. |
| Extrapyramidal Symptom (EPS) Scores (Schizophrenia Population: Baseline and Final Visit | Baseline and final visit (week 12) | EPS assesses 4 items: akathisia, dystonia, dyskinesia, and parkinsonism. Each item is scored on a 5-point severity scale ranging from 1 to 5, with higher score indicating greater severity of symptom. Change: score at final visit minus score at baseline. |
| Global Efficacy Evaluation Scores (Bipolar Population) | Final visit (week 12) | The Global Efficacy Evaluation assesses the final efficacy of ziprasidone on bipolar symptoms using a 5-point scale that ranges from very good to worsening of the original disease. |
| Global Efficacy Evaluation Scores (Schizophrenia Population) | Final visit (week 12) | The Global Efficacy Evaluation assesses the final efficacy of ziprasidone on schizophrenia symptoms using a 5-point scale that ranges from very good to worsening of the original disease. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Baseline and final visit | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline and final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline to final visit (week 12) | MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction. |
| Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | Baseline | CGI-S assesses the severity of the condition at baseline using a scale that ranges from (1)Normal, not ill at all to (7) Among the most severely ill patients. |
Participant flow
Pre-assignment details
Subjects enrolled had to have taken at least 1 dose of 40, 60, or 80 milligrams of ziprasidone. The study included subjects with diagnosed Type I or II bipolar disorder with manic and mixed episodes (n=223) and subjects with schizophrenia of up to moderate severity, either first diagnosed or repeated episodes (n=248).
Participants by arm
| Arm | Count |
|---|---|
| Ziprasidone Subjects had to have taken at least 1 dose of ziprasidone 40, 60, or 80 milligrams | 471 |
| Total | 471 |
Withdrawals & dropouts
| Period | Reason | FG000 |
|---|---|---|
| Overall Study | Adverse Event | 2 |
| Overall Study | At subject's request | 1 |
| Overall Study | Lack of Efficacy | 12 |
| Overall Study | Lost to Follow-up | 6 |
| Overall Study | Subject's untimely distrust of medicine | 1 |
Baseline characteristics
| Characteristic | Ziprasidone |
|---|---|
| Age, Customized 18-44 years | 294 Participants |
| Age, Customized <18 years | 2 Participants |
| Age, Customized 45-64 years | 152 Participants |
| Age, Customized >=65 years | 23 Participants |
| Sex/Gender, Customized Female | 271 Participants |
| Sex/Gender, Customized Male | 198 Participants |
| Sex/Gender, Customized Unspecified | 2 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 15 / 471 |
| serious Total, serious adverse events | 0 / 471 |
Outcome results
Primary
Brief Psychiatric Rating Scale (BPRS) Scores (Schizophrenia Population): Change From Baseline
BPRS is an 18-item scale with 11 general symptom items, 5 positive-symptom items, and 2 negative symptom items. The physician completes the BPRS, and each item is scored on a 7-point scale, with higher score indicating greater severity of symptom. Change: score at final visit minus score at baseline.
Time frame: Baseline to final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication. If any individual item was missing, the total score was set to missing. Here, overall number of participants analyzed signifies participants evaluable for this outcome measure.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Ziprasidone | Brief Psychiatric Rating Scale (BPRS) Scores (Schizophrenia Population): Change From Baseline | Baseline | 49.3 Score on scale | Standard Deviation 17.9 |
| Ziprasidone | Brief Psychiatric Rating Scale (BPRS) Scores (Schizophrenia Population): Change From Baseline | Final visit | 35.2 Score on scale | Standard Deviation 11.3 |
| Ziprasidone | Brief Psychiatric Rating Scale (BPRS) Scores (Schizophrenia Population): Change From Baseline | Change from baseline | -20.0 Score on scale | Standard Deviation 13.4 |
Primary
Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population)
CGI-S assesses the severity of the condition at baseline using a scale that ranges from (1)Normal, not ill at all to (7) Among the most severely ill patients.
Time frame: Baseline
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (1) Normal, not ill | 3 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (2) Borderline mentally ill | 5 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (3) Mildly ill | 19 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (4) Moderately ill | 57 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (5) Absolutely clearly ill | 101 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (6) Severely ill | 24 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | (7) Among the most extremely ill subjects | 0 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Bipolar Population) | Missing | 13 Participants |
Primary
Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population)
CGI-S assesses the severity of the condition at baseline using a scale that ranges from (1)Normal, not ill at all to (7) Among the most severely ill patients.
Time frame: Baseline
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (7) Among the most severely ill subjects | 0 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (1) Normal, not ill | 1 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (2) Borderline mentally ill | 5 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (3) Mildly ill | 14 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (4) Moderately ill | 63 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (5) Absolutely clearly ill | 105 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | (6) Severely ill | 33 Participants |
| Ziprasidone | Clinical Global Impression of Severity (CGI-S) Scores (Schizophrenia Population) | Missing | 23 Participants |
Primary
Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population)
CGI-C assesses change in severity of the conditionusing a scale that ranges from (1) very much improved to (7) very much worse. Higher score indicates increasing severity of disease.
Time frame: Final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (1) Very much improved | 40 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (5) Minimally worse | 1 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (7) Very much worse | 0 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (2) Much improved | 117 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (3) Minimally improved | 52 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (4) No change | 5 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | (6) Much worse | 3 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Bipolar Population) | Missing | 4 Participants |
Primary
Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population)
CGI-C assesses change in severity of the conditionusing a scale that ranges from (1) very much improved to (7) very much worse. Higher score indicates increasing severity of disease.
Time frame: Final visit (week 12)
Population: The schizophrenia full analysis set included all subjects who had been diagnosed with schizophrenia and had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (1) Very much improved | 22 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (2) Much improved | 125 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (3) Minimally improved | 76 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (4) No change | 14 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (5) Minimally worse | 1 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (6) Much worse | 3 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | (7) Very much worse | 0 Participants |
| Ziprasidone | Clinical Global Impressions Change (CGI-C) Scores (Schizoprenia Population) | Missing | 3 Participants |
Primary
Extrapyramidal Symptom (EPS) Scores (Schizophrenia Population: Baseline and Final Visit
EPS assesses 4 items: akathisia, dystonia, dyskinesia, and parkinsonism. Each item is scored on a 5-point severity scale ranging from 1 to 5, with higher score indicating greater severity of symptom. Change: score at final visit minus score at baseline.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication. If any individual item was missing, the total score was set to missing.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Ziprasidone | Extrapyramidal Symptom (EPS) Scores (Schizophrenia Population: Baseline and Final Visit | Baseline | 7.0 Score on scale | Standard Deviation 4.7 |
| Ziprasidone | Extrapyramidal Symptom (EPS) Scores (Schizophrenia Population: Baseline and Final Visit | Final visit | 4.4 Score on scale | Standard Deviation 2.9 |
Primary
Global Efficacy Evaluation Scores (Bipolar Population)
The Global Efficacy Evaluation assesses the final efficacy of ziprasidone on bipolar symptoms using a 5-point scale that ranges from very good to worsening of the original disease.
Time frame: Final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Global Efficacy Evaluation Scores (Bipolar Population) | Very good | 154 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Bipolar Population) | Good | 24 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Bipolar Population) | Average | 36 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Bipolar Population) | Poor | 4 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Bipolar Population) | Worsening of the original disease | 1 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Bipolar Population) | Missing | 3 Participants |
Primary
Global Efficacy Evaluation Scores (Schizophrenia Population)
The Global Efficacy Evaluation assesses the final efficacy of ziprasidone on schizophrenia symptoms using a 5-point scale that ranges from very good to worsening of the original disease.
Time frame: Final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Global Efficacy Evaluation Scores (Schizophrenia Population) | Good | 28 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Schizophrenia Population) | Average | 35 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Schizophrenia Population) | Poor | 7 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Schizophrenia Population) | Missing | 5 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Schizophrenia Population) | Very good | 166 Participants |
| Ziprasidone | Global Efficacy Evaluation Scores (Schizophrenia Population) | Worsening of the original disease | 3 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects who had been diagnosed with bipolar mania and had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline: Yes | 112 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline: No | 41 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline: Missing | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Final: Yes | 113 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Final: No | 37 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Final: Missing | 72 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Displeased | 32 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Mostly dissatisfied | 22 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Mixed | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Mostly satisfied | 34 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Pleased | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Could not be better | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Displeased | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Mostly dissatisfied | 24 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Mixed | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Mostly satisfied | 43 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Pleased | 40 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Displeased | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Mostly dissatisfied | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Mixed | 28 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Mostly satisfied | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Pleased | 47 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Could not be better | 7 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Displeased | 8 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Mostly dissatisfied | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Mixed | 19 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Mostly satisfied | 48 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Pleased | 59 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Could not be better | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Missing | 76 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Could not be worse | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Displeased | 19 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Mostly dissatisfied | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Mixed | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Mostly satisfied | 39 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Pleased | 50 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Could not be better | 7 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Missing | 70 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Displeased | 16 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Mostly dissatisfied | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Mixed | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Mostly satisfied | 48 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Pleased | 53 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects who had been diagnosed with bipolar mania and had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Could not be worse | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Displeased | 48 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Pleased | 14 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Could not be better | 5 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Mostly dissatisfied | 37 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Mixed | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Mostly satisfied | 21 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Missing | 71 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Displeased | 33 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Mostly dissatisfied | 41 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Mixed | 24 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Mostly satisfied | 24 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Pleased | 24 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Missing | 74 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Pleased | 60 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Could not be worse | 7 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Displeased | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Mostly dissatisfied | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Mixed | 22 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Mostly satisfied | 39 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Pleased | 50 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Could not be better | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Displeased | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Mostly dissatisfied | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Mixed | 22 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Mostly satisfied | 49 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Health? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Displeased | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Could not be worse | 5 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Displeased | 28 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Mostly dissatisfied | 28 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Mixed | 22 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Mostly satisfied | 33 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Pleased | 33 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Could not be better | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Mostly dissatisfied | 21 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Mixed | 32 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Mostly satisfied | 47 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Pleased | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Job? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Could not be worse | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Could not be better | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Displeased | 28 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Mostly dissatisfied | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Mixed | 19 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Mostly satisfied | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Pleased | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Displeased | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Mostly dissatisfied | 24 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Mixed | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Mostly satisfied | 49 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Pleased | 40 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Could not be worse | 8 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Displeased | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Mostly dissatisfied | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Mixed | 25 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Mostly satisfied | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Pleased | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Could not be better | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Displeased | 10 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Mostly dissatisfied | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Mixed | 28 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Mostly satisfied | 56 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Pleased | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Could not be better | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Missing | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Could not be worse | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Displeased | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Mostly dissatisfied | 19 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Mixed | 32 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Mostly satisfied | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Pleased | 35 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Could not be better | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Displeased | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Mostly dissatisfied | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Mixed | 34 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Mostly satisfied | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Pleased | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Could not be better | 3 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Displeased | 14 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Mostly dissatisfied | 12 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Mixed | 35 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Mostly satisfied | 37 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Pleased | 50 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Could not be better | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Displeased | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Mostly dissatisfied | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Mixed | 21 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Mostly satisfied | 54 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Pleased | 58 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Could not be better | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Displeased | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Mostly dissatisfied | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Mixed | 43 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Mostly satisfied | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Pleased | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Could not be better | 7 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Displeased | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Mostly dissatisfied | 12 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Mixed | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Mostly satisfied | 50 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Pleased | 55 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Could not be worse | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Displeased | 41 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Mostly dissatisfied | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Mixed | 32 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Mostly satisfied | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Pleased | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Could not be better | 10 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Could not be worse | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Displeased | 28 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Mostly dissatisfied | 22 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Mixed | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Mostly satisfied | 34 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Pleased | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects who had been diagnosed with bipolar mania and had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline: Yes | 88 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline: No | 66 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Final: Yes | 95 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Final: No | 54 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Last Week Have You Seen a Friend? | Final: Missing | 73 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Baseline: Yes | 7 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Baseline: No | 146 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Baseline: Missing | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Final: Yes | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Final: No | 143 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year Have You Been Accused of a Crime? | Final: Missing | 73 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline: Yes | 10 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline: No | 144 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Final: Yes | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Final: No | 141 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Bipolar Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Final: Missing | 72 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline: Yes | 113 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline: No | 64 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Final: Yes | 114 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Final: No | 58 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: Do You Have Anyone You Would Call a Close Friend? | Final: Missing | 72 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Mostly satisfied | 50 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Pleased | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Missing | 70 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Could not be worse | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Displeased | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Mostly dissatisfied | 37 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Mixed | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Mostly satisfied | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Pleased | 23 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Could not be better | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Could not be worse | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Displeased | 23 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Mostly dissatisfied | 35 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the Number and Quality of Your Friendships? | Final: Mixed | 36 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Mostly dissatisfied | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Mixed | 35 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Could not be worse | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Displeased | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Mostly satisfied | 43 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Pleased | 32 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Could not be better | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Could not be worse | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Displeased | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Mostly dissatisfied | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Mixed | 34 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Mostly satisfied | 61 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Pleased | 42 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Could not be better | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With the People You Live With? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Mostly satisfied | 41 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Pleased | 46 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Could not be better | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Could not be worse | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Displeased | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Mostly dissatisfied | 24 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Mixed | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Baseline: Missing | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Displeased | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Mostly dissatisfied | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Mixed | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Mostly satisfied | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Pleased | 51 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Could not be better | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Accomodation? | Final: Missing | 75 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Could not be worse | 8 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Displeased | 70 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Mostly dissatisfied | 39 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Mixed | 23 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Mostly satisfied | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Pleased | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Baseline: Missing | 72 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Displeased | 40 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Mostly dissatisfied | 54 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Mixed | 35 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Mostly satisfied | 20 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Pleased | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores(Schizophrenia Population) in Answer to: How Satisfied Are You With Your Financial Situation? | Final: Missing | 76 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline to final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Could not be worse | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Displeased | 18 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Mostly dissatisfied | 14 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Displeased | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Mostly dissatisfied | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Mixed | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Mostly satisfied | 40 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Pleased | 37 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Mixed | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Mostly satisfied | 66 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Pleased | 50 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Health? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Could not be worse | 5 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Displeased | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Mostly dissatisfied | 40 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Mixed | 39 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Mostly satisfied | 33 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Pleased | 22 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Baseline: Missing | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Displeased | 23 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Mostly dissatisfied | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Mixed | 33 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Mostly satisfied | 53 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Pleased | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Job? | Final: Missing | 71 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Displeased | 52 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Mostly dissatisfied | 46 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Mixed | 31 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Mostly satisfied | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Could not be better | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Baseline: Pleased | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Displeased | 15 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Mostly dissatisfied | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Mixed | 34 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Mostly satisfied | 72 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Pleased | 14 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Leisure Activities? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Could not be worse | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Displeased | 48 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Mostly dissatisfied | 37 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Mixed | 43 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Mostly satisfied | 30 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Pleased | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Could not be worse | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Displeased | 21 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Mostly dissatisfied | 23 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Mixed | 48 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Mostly satisfied | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Pleased | 14 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Life as a Whole Today? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication. Here, overall number of participants analyzed signifies participants evaluable for this outcome measure.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Could not be worse | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Displeased | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Mostly dissatisfied | 36 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Mixed | 44 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Mostly satisfied | 19 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Pleased | 17 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Could not be better | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Displeased | 20 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Mostly dissatisfied | 23 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Mixed | 54 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Mostly satisfied | 48 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Pleased | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Mental Health? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Could not be worse | 6 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Displeased | 34 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Mostly dissatisfied | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Mixed | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Mostly satisfied | 30 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Pleased | 27 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Could not be better | 8 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Could not be worse | 2 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Displeased | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Mostly dissatisfied | 14 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Mixed | 33 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Mostly satisfied | 63 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Pleased | 45 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Could not be better | 7 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Personal Safety? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Could not be better | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Could not be worse | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Displeased | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Mostly dissatisfied | 20 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Missing | 69 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Could not be worse | 3 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Displeased | 29 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Mostly dissatisfied | 32 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Mixed | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Mostly satisfied | 41 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Baseline: Pleased | 30 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Mixed | 40 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Mostly satisfied | 58 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Pleased | 43 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Relationship With Your Family? | Final: Could not be better | 2 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher score indicating greater satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia and who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Pleased | 13 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Could not be better | 1 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Displeased | 47 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Mostly dissatisfied | 44 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Could not be worse | 19 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Displeased | 59 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Mostly dissatisfied | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Mixed | 26 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Mostly satisfied | 20 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Could not be worse | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Mixed | 38 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Mostly satisfied | 20 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Pleased | 16 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Could not be better | 0 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: How Satisfied Are You With Your Sex Life? | Final: Missing | 70 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline: Yes | 87 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline: No | 86 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Baseline: Missing | 71 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Final: Yes | 98 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Final: No | 72 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Last Week Have You Seen a Friend? | Final: Missing | 74 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Baseline: Yes | 4 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Baseline: No | 173 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Baseline: Missing | 67 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Final: Yes | 5 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Final: No | 170 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been Accused of a Crime? | Final: Missing | 69 Participants |
Primary
Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence?
MANSA is a 16-item self-assessment of satisfaction with quality of life. Items are rated on a 7-point scale, with higher number indicating higher satisfaction.
Time frame: Baseline and final visit (week 12)
Population: The schizophrenia full analysis set included all subjects with a diagnosis of schizophrenia who had received at least 1 dose of study medication.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline: Yes | 11 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline: No | 165 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Baseline: Missing | 68 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Final: Yes | 9 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Final: No | 166 Participants |
| Ziprasidone | Manchester Short Assessment of Quality of Life (MANSA) Scores (Schizophrenia Population) in Answer to: In the Past Year, Have You Been a Victim of Physical Violence? | Final: Missing | 69 Participants |
Primary
Montgomery Asberg Depression Rating Scale (MADRS) Scores (Bipolar Population): Change From Baseline
MADRS measures treatment effect on depression severity. MADRS assesses apparent and reported sadness, inner tension, sleep, appetite, concentration difficulties, lassitude, inability to feel, pessimistic thoughts, and suicidal thoughts. Higher score indicates greater severity of disease. Change: score at final visit minus score at baseline.
Time frame: Baseline to final visit (12 weeks)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication. If any individual item was missing, the total score was set to missing. Here, overall number of participants analyzed signifies participants evaluable for this outcome measure.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Ziprasidone | Montgomery Asberg Depression Rating Scale (MADRS) Scores (Bipolar Population): Change From Baseline | Baseline | 26.2 Score on scale | Standard Deviation 20.3 |
| Ziprasidone | Montgomery Asberg Depression Rating Scale (MADRS) Scores (Bipolar Population): Change From Baseline | Final visit | 11.6 Score on scale | Standard Deviation 9.1 |
| Ziprasidone | Montgomery Asberg Depression Rating Scale (MADRS) Scores (Bipolar Population): Change From Baseline | Change from baseline | -14.6 Score on scale | Standard Deviation 16.1 |
Primary
Young Mania Rating Scale (YMRS) Scores (Bipolar Population): Change From Baseline
The YMRS is an 11-item questionnaire that rates the severity of bipolar disorder, with higher score indicating greater severity of disease. Change: score at final visit minus score at baseline.
Time frame: Baseline to final visit (12 weeks)
Population: The bipolar full analysis set included all subjects with a diagnosis of bipolar mania who had received at least 1 dose of study medication. If the final visit measurement was missing, the follow-up measurement could be carried forward. If any individual item was missing, the total score was set to missing. Here, overall number of participants analyzed signifies participants evaluable for this outcome measure.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Ziprasidone | Young Mania Rating Scale (YMRS) Scores (Bipolar Population): Change From Baseline | Baseline | 26.6 Score on scale | Standard Deviation 12.6 |
| Ziprasidone | Young Mania Rating Scale (YMRS) Scores (Bipolar Population): Change From Baseline | Final visit | 10.8 Score on scale | Standard Deviation 8.3 |
| Ziprasidone | Young Mania Rating Scale (YMRS) Scores (Bipolar Population): Change From Baseline | Change from baseline | -15.6 Score on scale | Standard Deviation 9.4 |