Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery

Opioid-potentiated Volative Anaesthetic(Sevoflurane)Compared to Remifentanil and Propofol During Abdominal Aortic Aneurysm Surgery

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00538421

Acronym

ABSENT

Enrollment

193

Registered

2007-10-02

Start date

2008-03-31

Completion date

2013-03-31

Last updated

2013-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal, Aneurysm, Aortic Diseases, Surgery

Keywords

propofol, Anaesthesia, Sevoflurane, Abdominal, Aortic, Aneurysm

Brief summary

Comparing 2 different anaesthetic methods during abdominal aortic aneurysm surgery. The patients will be followed up 30 days postoperative. Number of patients included will be 200. Perioperative details will be analyzed.

Interventions

DRUGPropofol

Infusion intravenously (IV) 0-10 mg/kg/h

DRUGSevoflurane

0,7-1,5 MAC

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who are planned for open, elective abdominal aortic aneurysm surgery. * ASA group 1-4.

Exclusion criteria

* Patients below 18 years. * Patients who are included in other pharmaceutical studies. * Opioids-, benzodiazepins-, antiepileptic drugs-, alcohol- and α2-agonists abuse. * Pregnant and breastfeeding women. * Patients with familiar history of malignant hyperthermia. * Patients with known hypersensitivity for opioids, propofol or volative anaesthetics. * Patients with considerable arrythmia (atrial fibrillation /atrial flutter is acceptable). Uncontrolled hypertension, serious psychiatric disease. * Patients with unstable angina pectoris or myocardial infarction last month before inclusion. * Acute abdominal aortic surgery. Acute dissection or rupture. * Planned laparoscopic abdominal aortic aneurysm surgery.

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026