Nausea, Vomiting
Conditions
Brief summary
The purpose of this study is to determine whether powdered ginger root (encapsulated ginger) is effective for reducing the frequency, duration and severity of both acute and delayed nausea and vomiting.
Interventions
DIETARY_SUPPLEMENTGinger
Capsule, 1000 mg, BID, 3 days
DIETARY_SUPPLEMENTPlacebo
Capsule, 1000 mg, BID, 3 days
Sponsors
National Research Institute of Tuberculosis and Lung Disease, Iran
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Must be able to give written informed consent. * Have a diagnosis of cancer and currently receiving chemotherapy containing cisplatin (any dose). * Scheduled to receive antiemetics: granisetron (kytril), hydrocortisone. * Must be able to complete study questionnaires. * Must be able to swallow capsules.
Exclusion criteria
* Have no clinical evidence of current or impending bowel obstruction. * Concurrent radiotherapy that is classified as high or intermediate risk of causing emesis. * Pregnant or lactating. * Patients taking therapeutic doses of coumadin (individuals on low-dose to maintain peripheral or central venous catheters are allowed), aspirin (individuals taking low-dose 80mg aspirin are allowed), or heparin. * Patients with a history of a bleeding disorder(s) in past 6 months and those experiencing thrombocytopenia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea, Vomiting | 3 days |
Countries
Iran
Outcome results
None listed