Hordeolum
Conditions
Keywords
Antibiotics, hordeolum
Brief summary
To compare the effectiveness of combined antibiotic ophthalmic solution (neomycin sulfate, polymyxin B sulfate and gramicidin) with placebo (artificial tear) in the treatment of hordeolum after incision and curettage
Detailed description
Hordeolum is a common eyelid disease. In case of mass, I&C is required but role of antibiotic after I&C is not clear. It may not need in post drainage period.
Interventions
DRUGneomycin sulfate, polymyxin B sulfate and gramicidin
to the effected eye 4 times a day
DRUGArtificial tear
4 times daily
Sponsors
Chulalongkorn University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* at least 5-millimeters hordeolum * the onset within 7 days
Exclusion criteria
* previous incision and curettage of the same site within 1 month or more than 3 times * lesions in the adjacent areas suggesting of complications associated with hordeolum such as preseptal cellulitis or blepharitis * The patients with immunodeficiency, history of bleeding tendency * allergy to aminoglycoside, polymyxin B, gramicidin, xylocaine and povidone iodine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain scale | 1,3,7 days after treatment |
Secondary
| Measure | Time frame |
|---|---|
| Mass size and duration of cure | 1, 3, 7, 30 days after treatment |
Countries
Thailand
Contacts
Primary ContactParima Hirunwiwatkul, MD
Backup ContactPuangphet Chalermphanich, MD
Outcome results
None listed