CBT to Treat Depression in Renal Patients

Effectiveness of Cognitive Behavioral Therapy in Patients With End-Stage Renal Disease in Hemodialysis and With Depression

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00530296

Acronym

CBTRPat

Enrollment

Registered

2007-09-17

Start date

2005-06-30

Completion date

2008-06-30

Last updated

2007-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, End Stage Renal Disease

Keywords

Depression, End stage renal disease, Quality of Life, Cognitive Behavioral Therapy

Brief summary

The purpose of this study is to determine whether Cognitive Behavioral Therapy is effective in the treatment of depression in patients with end-stage renal disease in hemodialysis therapy

Detailed description

Depression is a persistent problem among patients with end-stage renal disease and it does not tend to improve over time. The implementation of effective interventions to treat and prevent recurrence of depressive episodes is needed. The objectives of this study are: 1)the detection of Major Depression in hemodialysis patients; 2)to allocate patients with depression in two groups: structured program of treatment with CBT (group therapy)and control group (conventional psychotherapy at the dialysis unit); and 3)to verify whether after 3 months of CBT there was a remission of depressive symptoms and a improvement of the quality of life in the CBT group.

Interventions

BEHAVIORALCognitive Behavioral Therapy

Group therapy, 12 sessions (90 minutes each, one session per week) manual Coping with depression course

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients with a diagnosis of Chronic renal disease (end stage) in hemodialysis for at least 3 months * Diagnosis of Major depression disorder (4 or more clinical criteria in MINI and a BDI score of 10 or more)

Exclusion criteria

* Patients in process of renal transplant with (living donor) * Psychiatric comorbidity * Cognitive impairment or mental retardation * Current substance abuse * Heart failure, angina pectoris, arrhythmias

Design outcomes

Primary

Measure	Time frame
Mini International Neuropsychiatric Interview (MINI-DSM-IV) Beck Depression Inventory (BDI)	Baseline; 3 months (end of intervention); follow-up (6 months after the end of the intervention)

Secondary

Measure	Time frame
Kidney Disease and Quality of Life Short-form (KDQOL-SF)	Baseline; 3 months (end of intervention); follow-up (6 months after the end of the intervention)

Countries

Brazil

Contacts

Primary ContactPriscila S Duarte, MA

psduarte@nefro.epm.br55-17-3231 5660

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026