Overweight
Conditions
Keywords
Overweight, Obesity, Weight loss, Medium chain triglycerides, Cardiovascular disease risk
Brief summary
The primary aim of this research project is to determine whether the incorporation of food products containing medium chain triglyceride (MCT) oil in a weight-loss program results in a different degree of weight-loss and total and regional fat mass loss than the incorporation of extra light olive oil. The secondary goals are to test whether there are differences in in metabolic risk profile changes between the 2 diets. We hypothesize that men and women who consumed MCT oil as part of their weight loss program will lose more weight and body fat than those who consume olive oil in their weight loss diet.
Interventions
DIETARY_SUPPLEMENTWeight loss
Weight loss study including consumption of either 22-25 g of medium chain triglyceride oil or olive oil
Sponsors
International Life Sciences Institute
University of Alabama at Birmingham
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
19 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* body mass index 27-33 kg/m2 * pre-menopausal women * weight stable for at least 6 months * normal score on Brief Symptoms Inventory questionnaire
Exclusion criteria
* chronic disease * weight loss treatment * medication known to affect body weight * unstable blood pressure, glucose, lipid levels
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in body weight and fat mass, change in plasma lipid concentrations, fasting glucose and fasting insulin | 16 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change in blood pressure, change in fat-free mass | 16 weeks |
Countries
United States
Outcome results
None listed