Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00529776

Enrollment

150

Registered

2007-09-14

Start date

2005-09-30

Completion date

2008-05-31

Last updated

2008-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia, Ventilator-Associated

Keywords

Prevention of ventilator associated pneumonia

Brief summary

Hypothesis: Ventilator associated pneumonia (VAP) in critically ill patients may be prevented by continuous lateral rotation therapy (CLRT) using specially designed, motor driven beds. Patients are randomized to CLRT or supine position if mechanically ventilated and not suffering from pneumonia or ARDS within 48 hours after intubation. Prophylaxis of VAP is standardized in both groups. Primary endpoint is incidence of VAP, secondary endpoints are length of ventilation, length of stay and mortality.

Interventions

PROCEDUREContinuous lateral rotation therapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 89 Years

Healthy volunteers

Inclusion criteria

* Mechanically ventilated * Intubated not longer than 48 h * Medical cause for ICU admission * Expected to be ventilated for \> 48 hours

Exclusion criteria

* Pneumonia or ARDS present * Postoperative patient

Design outcomes

Primary

Measure	Time frame
Ventilator associated pneumonia	—

Secondary

Measure	Time frame
Length of hospital stay	—
Length of mechanical ventilation	—
ICU and hospital Mortality	—

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026