Proliferative Diabetic Retinopathy
Conditions
Keywords
Laser Photocoagulation, Pain relief
Brief summary
The study wants to show if the medication etoricoxib 120 mg have reduces the patients pain during the laser photocoagulation, for diabetic retinopathy.
Detailed description
To do so we compare two group of patients, randomized 1:1, one use the medication(etoricoxib) and other use placebo and they quantify the pain using the Pain visual analogue scale
Interventions
DRUGplacebo (Control Group)
Both medication have been given to the patients in both groups 1 hour prior the laser photocoagulation
Both medication have been given to the patients in both groups 1 hour prior the laser photocoagulation
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
17 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with diabetic retinopathy that needs laser photocoagulation for the first time
Exclusion criteria
* Younger than 17 * Signs and symptoms of liver dysfunction or abnormal liver function tests * Gastrointestinal diseases * Pregnant women * Edema * Pre-existing cardiac insufficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The group taking the etoricoxib feel less pain then the group taking placebo | After each laser session |
Countries
Brazil
Outcome results
None listed