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Gallbladder Cholesterolosis, Body Mass Index and Serum Cholesterol and Triglycerides

Association of Gallbladder Cholesterolosis to Body Mass Index and Levels of Serum Cholesterol and Triglycerides.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00528632
Enrollment
406
Registered
2007-09-12
Start date
2008-03-31
Completion date
2009-07-31
Last updated
2011-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallbladder Cholesterolosis, Gallstones

Keywords

Gallstones, Gallbladder, Cholesterolosis, Serum cholesterol, triglycerides, Body Mass Index

Brief summary

Cholesterolosis is a common finding in biopsy specimens of gallbladders surgically removed for cholelithiasis. To the best of the investigators knowledge no study has analyzed the relationships of Body Mass Index, serum Cholesterol and Triglycerides and gallbladder cholesterolosis. The purpose of this study is to analyze and find relations between gallbladder cholesterolosis, Body Mass Index, serum cholesterol and triglycerides.

Detailed description

A prospective database including the following variables was filled out: * Age * Gender * Diagnosis * Weight * Height * Body Mass Index * Histopathological results (Biopsy) * Serum cholesterol * Serum triglycerides All elective patients older than 15 years of age submitted to cholecystectomy for symptomatic gallstones were included. Plasma cholesterol and triglycerides levels were measured 5 to 7 days before surgery. Only patients with chronic cholecystitis and with cholesterolosis according to the histology of the surgical specimen were included, we did not include any patient with acute cholecystitis or gallbladder cancer.

Interventions

OTHERSpecimen biopsy and serum laboratory tests

Biopsy of the surgical specimens (gallbladder) submitted after cholecystectomy Laboratory tests measuring levels of plasma total cholesterol and triglycerides

Sponsors

Cirujanos la Serena
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients submitted to elective cholecystectomy * Histopathological report of gallbladder cholesterolosis * Histopathological report of chronic cholecystitis * Patients older than 15 years of age

Exclusion criteria

* Patients younger than 15 years of age * Pathological report missing from the hospital records

Countries

Chile

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026