Laser Acupuncture Against Nausea in Children

Laser Acupuncture to Alleviate Nausea and Vomiting in Children and Adolescents Receiving Highly Emetogenic Chemotherapy. A Prospective, Double-Blinded, Placebo-Controlled Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00528554

Enrollment

Registered

2007-09-12

Start date

2007-09-30

Completion date

2009-09-30

Last updated

2007-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Nausea, Vomiting

Keywords

CINV, chemotherapy induced nausea and vomiting (CINV)

Brief summary

To investigate whether nonthermal low level laser acupuncture has beneficial effects on nausea and vomiting in children receiving highly emetogenic chemotherapy for a malignant solid tumor. In a previous crossover study comparing needle acupuncture to no intervention in an otherwise similar setting we found beneficial effects, but this trial was not even single-blinded and therefore the results are questionable. The hypothesis is that active laser acupuncture is more effective than placebo laser acupuncture concerning episodes of retching/vomiting (primary outcome measure) and rescue antiemetic medication (secondary outcome measure) with a fix standard antiemetic medication

Interventions

PROCEDURElaser acupuncture

laser acupuncture according to traditional chinese medicine criteria, energy dosage 1J/point, average of 8 points to be treated, once daily during chemotherapy course

PROCEDUREplacebo laser acupuncture

laser acupuncture according to traditional chinese medicine criteria, average of 8 points to be treated, once daily during chemotherapy course

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

No minimum to 17 Years

Healthy volunteers

Inclusion criteria

* Age 0-17, * Highly emetogenic chemotherapy with at least 4 similar courses of chemotherapy concerning applied drugs (equivalent dosages)

Exclusion criteria

* Age older than 17 years, * Participation in another clinical trial on supportive care

Design outcomes

Primary

Measure	Time frame
episodes of retching/vomiting per day during 1 chemotherapy course	1 chemotherapy course (5 days)

Secondary

Measure	Time frame
rescue antiemetic medication during 1 chemotherapy course	1 chemotherapy course (5 days)

Countries

Germany

Contacts

Primary ContactSven Gottschling, MD

kisgot@uniklinikum-saarland.de+49 6841 1628399

Backup ContactNorbert Graf, MD, PhD

kingra@uniklinikum-saarland.de+49 6841 1628397

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026