Prone Position for Non-intubated Patients With Acute Respiratory Failure

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00526981

Enrollment

Registered

2007-09-10

Start date

2007-09-30

Completion date

Unknown

Last updated

2011-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Failure

Brief summary

The study will test the hypothesis that the prone position can be used to reduce the need for intubation and mechanical ventilation in patients with acute respiratory failure.

Interventions

OTHERProne position

Prone position during spontaneous breathing.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* bilateral pulmonary infiltrates or unilateral infiltrates involving more than one lobe on CXR * PaO2/FIO2 \< 40 kPa * RR \> 25, or attending intensivist considering likelihood of intubation \> 50%

Exclusion criteria

* unsuited for the prone position * fulfilled inclusion criteria for more than 5 days (120 h) * immunosuppression * chronic lung disease * decision of withdrawal or limitation of therapy * pulmonary infiltrates of cardiac origin * decreased GCS level * PaCO2 \> 10 * attending intensivist considering the patient unsuited for the prone position * BMI \> 33

Design outcomes

Primary

Measure	Time frame
Need for intubation and mechanical ventilation	Duration of hospital stay

Countries

Sweden

Contacts

Primary ContactJohan Petersson, MD

johan.petersson@karolinska.se+4685172066

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026