Does Oral Magnesium Substitution Relieve Pregnancy Induced Leg Cramps ?

Does Oral Magnesium Substitution Relieve Magnesium Induced Leg Cramps ?

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00525317

Enrollment

Registered

2007-09-05

Start date

2002-01-31

Completion date

2004-09-30

Last updated

2013-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cramps

Keywords

Pregnancy, Magnesium, Leg Pain

Brief summary

This is a trial of treatment with tablets containing magnesium for leg cramps in pregnancy.

Detailed description

Healthy pregnant women between 18 and 36 weeks of pregnancy suffering from leg cramps at least twice a week were treated with magnesium tablets or placebo for two weeks, 120 mg x 3 daily.

Interventions

DRUGNycoplus Magnesium (120 mg x 3 daily for 2 weeks)

120 mg x 3 or placebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 38 Years

Healthy volunteers

Inclusion criteria

* Pregnant women with recurrent leg cramps (at least twice a week). * No disease according to helath certificate. Written participation consent must be signed. * Linguistic ability demanded: Norwegian as the first language. Gestation length more than 17 weeks, less than 36 weeks.

Exclusion criteria

* Twin pregnancy. * Oedema. * Pre-eclampsia. * Magnesium supplementation beyond the trial treatment.

Design outcomes

Primary

Measure	Time frame
Pain intensity and frequency	end of study

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026