Allergic, Perennial, Rhinitis
Conditions
Keywords
levocetirizine dihydrochloride, Xyzal tablets
Brief summary
Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis.
Interventions
Sponsors
UCB Pharma
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Male ore female, 16 to 60 years old (inclusive) * two-year history of allergic rhinitis due to house dust mite
Exclusion criteria
* An ear, nose or throat (ENT) infection * asthma requiring daily drug therapy other than ß2 inhaled agonists taken prn * atopic dermatitis or urticaria requiring an antihistamine or corticosteroid treatment * an associated ENT disease * use of decongestants * nasal or ocular topical treatment * desensitivation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total 5 Symptom Score (T5SS) rated by the investigator | 2 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Investigators global efficacy evaluation at the end of treatment; subject's rating of T5SS and individual symptoms (over the last 24 hours) over first week and the total 2 weeks treatment period; the Symptoms Score Reducing Index (SSRI). | 2 weeks |
Outcome results
None listed