Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infectionsin Adults

Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infections and Time to Re-Implantation in Adults

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00524108

Enrollment

350

Registered

2007-09-03

Start date

2007-08-31

Completion date

2010-12-31

Last updated

2012-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection, Ventriculoperitoneal Shunt

Keywords

shunt, internal ventriculoperitoneal

Brief summary

The objectives of this study are: * To describe the incidence of clinical features in adults with internal ventriculoperitoneal (VP) shunt infections, * To determine the validity of laboratory parameters in adults with internal ventriculoperitoneal shunt infections and * To evaluate the relationship between the timing of shunt re-implantation with the rates of relapse and secondary infection.

Detailed description

Information from medical records of patients seen by the PI will be collected and analyzed to describe the incidence of clinical features in adults with internal ventriculoperitoneal shunt infections, to determine the validity of laboratory parameters in adults with internal ventriculoperitoneal shunt infections and to evaluate the relationship between the timing of shunt re-implantation with the rates of relapse and secondary infection.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults (age \>= 18 yrs) with VP shunts (ventriculoatrial \[VA\], and other cerebrospinal fluid \[CSF\] catheters will not be included). * Cases will include patients with a diagnosis of VP shunt infection. * Controls will be patients with a clinical suspicion of shunt infections with negative CSF cultures.

Exclusion criteria

* Patients with meningitis from community acquired organisms (e.g. Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes and Haemophilus Influenzae).

Countries

United States

Outcome results