Dilated Cardiomyopathy (DCM)
Conditions
Brief summary
Dilated cardiomyopathy (DCM) affects about 200,000 Canadians. Eighty percent of these cases are of unclear cause, often occuring in families. We believe that mutations in specific already-identified genes contribute to DCM in Quebec and that certain mutations may account for a significant proportion of cases due to the well-documented founder effect. Two hundred patients with DCM followed in our Heart Function Clinic will be approached for one blood sample at their routine clinic visit to test this hypothesis. The samples will be tested in the Laboratory of Cardiovascular Genetics at the Royal Victoria Hospital.
Interventions
OTHERblood test
looking at DNA
Sponsors
McGill University Health Centre/Research Institute of the McGill University Health Centre
Study design
Observational model
FAMILY_BASED
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Followed at MUHC Heart Function Centre * Documented EF of less than or equal to 35% and an enlarged heart with a left ventricular end-diastolic size of greater than 6 cm. * Patient's written consent
Exclusion criteria
* Patients with a known underlying condition that results in a weakened and enlarged heart * Patients unable to read and understand the consent form * Patients who do not wish to participate
Countries
Canada
Contacts
Primary ContactNadia S Giannetti, MD
Outcome results
None listed