Hip Fracture, Malnutrition
Conditions
Keywords
Elderly, Osteoporosis, hip fracture, malnutrition, nutritional support
Brief summary
Hip fractures are highly prevalent and are expected to increase due to the ageing population. Malnutrition is often present in these patients and is associated with prolonged convalescence, lower mobility, lower mental function, lower quality of life and higher complication rate. Nutritional intervention starting soon after hospital admission might reduce complication rate and total length-of-stay by improving nutritional and functional status. Research questions are: 1. Does nutritional intervention reduce total length-of-stay? 2. Is nutritional intervention cost-effective? 3. Can nutritional screening contribute to targeting of nutritional intervention, and thereby reduce costs without loss of effectiveness? Patients randomized to the intervention group will receive oral nutritional supplements (protein and energy enriched) and regular dietetic counselling during hospitalisation and after discharge at patients' homes for 3 months. Patients in the control group will receive usual nurse and dietetic care. Outcome measurements will be taken at baseline, 3 months and 6 months after inclusion.
Interventions
DIETARY_SUPPLEMENTCubitan
400 ml/d
Sponsors
ZonMw: The Netherlands Organisation for Health Research and Development
Maastricht University Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Admission to one of the participating hospitals because of a proximal femur fracture * Age 55 years and older
Exclusion criteria
* Periprosthetic or pathologic fracture * Diseases of bone metabolism, e.g. Paget, primary/secondary bone tumors, hyperparathyroidism, M. Kahler * Life expectation of less than one year due to underlying disease (e.g. cancer) * Presence of dementia or other severely impaired cognitive function * Inability to communicate in Dutch language * Nutritional intervention prior to admission * Patients who are bedridden * Patients who are too ill or for any other reason not able to participate adequately in follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total length of hospital stay and rehabilitation clinics | baseline, 3 months and 6 months after inclusion |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional status, hip functionality, physical disability, fatigue, quality of life. | baseline, 3 months and 6 months after inclusion |
| Cost questionnaire, informal care questionnaire. | baseline, 3 months and 6 months after inclusion |
| Rate of complications | baseline, 3 months and 6 months after inclusion |
Countries
Netherlands
Outcome results
None listed