Community Acquired Pneumonia., Acute Hypoxemic Respiratory Failure
Conditions
Keywords
Severe community-acquired pneumonia, Noninvasive mechanical ventilation, Acute hypoxemic respiratory failure.
Brief summary
The purpose of this study is to determine whether the noninvasive ventilation is more effective in the treatment of severe comunity acquired pneumonia in comparison with the conventional mechanical ventilation with orotracheal intubation.
Interventions
Sponsors
Hospital Privado del Sur
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
The criteria for the diagnosis of SCAP included: * Blood systolic pressure lower than 90 mmHg or blood diastolic pressure lower than 60 mmHg * RR higher than 30 breaths per minute * PaO2/FiO2 lower than 250 while breathing through a Venturi mask with a 50% inspired oxygen fraction (FiO2) * Bilateral or multiple lobar infiltrations evidenced by thorax X-ray, and * Use of vasopressor drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary aim of this study was to compare the effects of NIMV on mortality rate and length of stay at the ICU with the effects of CMV | 3 years |
Secondary
| Measure | Time frame |
|---|---|
| The secondary aims were to evaluate the incidence and the complications of OTI as well as to compare the improvements in the gas exchange. | 3 years |
Countries
Argentina
Outcome results
None listed