Pain
Conditions
Keywords
Pain, Brachial Plexus Anesthesia, Plasma Lidocaine Levels, Ultrasound
Brief summary
Pain Clinic patients undergoing physiotherapy for rehabilitation often have arm freezing performed. The quality of physiotherapy is felt to be superior with good pain control. The quality of the freezing is felt to be better when it is done with ultrasound guidance. We are able to use less drug to achieve the same result. For this reason, we are doing a study to look at the level of freezing drug that accumulates in the body. We feel that the drug levels will be significantly different. We also feel that the time-to-peak drug level will be different than with traditional arm freezing procedures.
Interventions
DRUGLidocaine
Lidocaine, 5 mg/kg, via needle placed adjacent to brachial plexus with ultrasound, dosing separated by 1 week, 2 doses in total, one block will contain 5 mcg/kg of adrenaline
Sponsors
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* patients undergoing brachial plexus anesthesia as part of disease management who have consented to participate in the study
Exclusion criteria
* Contraindication to brachial plexus anesthesia * Informed consent not obtained
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lidocaine drug level | 40 minutes |
Secondary
| Measure | Time frame |
|---|---|
| brachial plexus block quality | 30 minutes |
| Physiotherapy quality | within 2 hours |
Countries
Canada
Outcome results
None listed