Pregnancy
Conditions
Keywords
Myocardial strain, Myocardial function, Pregnancy, Postpartum, Echocardiography, Myocardial adaptation to pregnancy, Systolic function, Diastolic function
Brief summary
The purpose of this echocardiographic study is to restudy the longitudinal changes in cardiac size and function during and after pregnancy in healthy women using relatively new parameters of systolic and diastolic function as well as classical measures of left ventricle (LV) function using contemporary echocardiographic machines. We, the researchers at Hillel Yaffe Medical Center, will assess diastolic function and its possible relation to shortness of breath.
Detailed description
A comprehensive echocardiographic study of the heart will be conducted in the first, second and third trimesters of pregnancy and 3 months postpartum. Determination of left ventricular dimensions, transvalvular Doppler flow, ejection fraction, stroke volume, cardiac output, pulmonary vein flow, tissue Doppler, flow propagation, global and segmental strain parameters, timing of peak strain and various parameters of diastolic function will be obtained. From these data normal values for various stages of pregnancy will be determined as well as range for changes expected during longitudinal follow-up will be determined.
Interventions
None listed
Sponsors
Hillel Yaffe Medical Center
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
Yes
Inclusion criteria
* Healthy women * First trimester of a normal pregnancy * Normal baseline echocardiogram
Exclusion criteria
* Pregnancy with more than one fetus. * Any hemodynamically significant cardiac condition * Any known systemic disease * Poor quality echocardiogram
Countries
Israel
Contacts
Primary ContactDavid S Blondheim, MD
Outcome results
None listed