Efficacy and Safety of TJ-100 in the Treatment of Chronic Constipation

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00522093

Enrollment

Registered

2007-08-29

Start date

2007-08-31

Completion date

2008-03-31

Last updated

2011-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Constipation

Keywords

constipation

Brief summary

TJ-100, a Japanese herbal medicine, is clinically effective in postoperative ileus. So it may activate bowel movement. This study will test the efficacy and safety of TJ-100 in the treatment of patients with chronic constipation.

Interventions

DRUGTJ-100

TJ-100 2.5g three times per day for 6 weeks

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 89 Years

Healthy volunteers

Inclusion criteria

* chronic constipation defined as less than 3 spontaneous bowel movement frequencies per week * had symptoms of abdominal bloating or discomfort

Exclusion criteria

* mechanical bowel obstruction * clinically systemic disease-induced constipation * pregnancy

Design outcomes

Primary

Measure	Time frame
Bowel movement frequency, rescue medication use, symptom assessments, bowel gas volume measurement, adverse events	baseline (4 weeks)

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026