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Detection and Treatment of Depression in Patients Admitted to the General Hospital

Status
UNKNOWN
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00521911
Enrollment
60
Registered
2007-08-28
Start date
2007-08-31
Completion date
2008-12-31
Last updated
2008-12-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Depressive Disorder

Keywords

Intervention Studies, Randomized Controlled Trials, Cognitive Therapy, Hospitals, General, Prevalence

Brief summary

Depression is a common disorder among patients with a somatic illness admitted to the general hospital. Patients with depression do worse in terms of their somatic symptoms or functioning that those without depression. They also stay in the hospital for longer. That is the reason that we are interested to know whether patients with depression do better if their depression is recognised earlier and treated appropriately. We would like to find out which questionnaires are most suitable in clinical practice to help pick up patients with a depression. In addition, we would like to know whether a short-term psychological treatment of depression would be of any help. We hope to be able to show that this treatment would not only result in a reduction of depressive symptoms, but also in a better and quicker recovery of the somatic illness. The treatment will consist of 6 to 9 weekly sessions of one hour, conducted by a cognitive behavioural assistant. Initially, the treatment will take place in the hospital. When patients are discharged, treatment sessions will continue at home. The treatment will focus on things like recognising and challenging unhelpful thoughts, planning of activities, and testing out of predictions by setting up behavioural experiments. Three monthly booster sessions will be offered to help patients to maintain their gains and prevent relapse. We will reassess the symptoms of the patients at three and six months after the end of treatment.

Interventions

BEHAVIORALCognitive Behavioural Therapy

Sponsors

Radboud University Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Depressive Disorder

Exclusion criteria

* Severe Physical Disfunction * Severe Cognitive Disfunction * Speech and/or Hearing Disorder * Limited knowledge of the Dutch language

Design outcomes

Primary

MeasureTime frame
Depressive Disorder Physical symptoms9 months

Secondary

MeasureTime frame
- Functional impairment (RAND 36) - Cost-effectiveness (TiC-P) - Quality of Life (EQ5D)9 months

Countries

Netherlands

Contacts

Primary ContactMatthijs W. Beltman, MSc
mw.beltman@psy.umcn.nl+31 (0)24 3668008

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026