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Physical Activity as an Aid for Smoking Cessation

Physical Activity as an Aid for Smoking Cessation: a Randomized Controlled Trial

Status
Terminated
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00521391
Acronym
PHASMO
Enrollment
600
Registered
2007-08-27
Start date
2003-04-30
Completion date
2005-12-31
Last updated
2007-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Physical Activity, Tobacco Dependence

Keywords

smoking cessation, nicotine, physical activity

Brief summary

Including a tailored moderate-intensity physical activity intervention in a standard smoking cessation treatment program (pharmaceutical treatment and counseling) increases the chances of quitting and reduces nicotine withdrawal symptoms, negative moods, stress, and weight gain.

Detailed description

The main objective is to determine whether a tailored physical activity intervention involving moderate-intensity exercise is an added value to a standard smoking cessation intervention in term of likelihood of smoking abstinence. The secondary objectives are 1) to determine whether this tailored physical activity intervention prevents weight gain, reduces withdrawal symptoms, stress and improve mood and self-confidence in quitting; 2) to assess the effect of this tailored physical activity intervention on body composition and leptin concentration. We assess this intervention in a randomized controlled trial of 600 sedentary adults regular smokers recruited from the community allocated into one of the two groups (intervention group vs. control group) during a 10-week period and 3 follow-up visits (6 and 12 months follow-up). All subjects (intervention and control groups) participate in a smoking cessation program composed of a pharmacological treatment (including nicotine replacement therapy) and counseling. The intervention group attend the 10-week physical activity program blending moderate-intensity exercise (Swiss nationwide implemented program entitled Allez Hop!) and lifestyle physical activity and the control group a 10-week health education program to ensure equal contact condition.

Interventions

OTHERAllez Hop

a tailored physical activity intervention involving moderate-intensity exercise

Sponsors

University of Lausanne Hospitals
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1. Current daily smoker \>10 or more cigarettes per day 2. Having smoked (on average \> 10 cigarettes/day) regularly for at least 3 years 3. Age between 18 and 65 years 4. Sedentary lifestyle defined as less than 20 minutes a day of moderate-intensity physical assessed by the Swiss Baseline Questionnaire.

Exclusion criteria

1. Current pharmacological agent use to quit smoking 2. Medical problems that would alter training responses: arthritis, heart disease, and orthopedic problems 3. Presence of an unstable medical condition 4. Current or recent major cardiovascular event, such as recent myocardial infarction (\>12 months) or stroke, angina pectoris, major arrhythmia 5. Current psychiatric illness 6. Alcohol (\> 4 drinks/day for men and \> 3 drink/d. for women), or/and other substance abuse 7. Current or planned pregnancy 8. Systematic skin disease

Design outcomes

Primary

MeasureTime frame
smoking cessation12 months

Secondary

MeasureTime frame
weight change12 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 31, 2026