Abdominal Obesity
Conditions
Brief summary
The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.
Interventions
Sponsors
Canadian Institutes of Health Research (CIHR)
Queen's University
Study design
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
65 Years to 80 Years
Inclusion criteria
* Men and women between 65 and 80 years of age. * Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic. * We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.
Exclusion criteria
* Smokers and diabetics. * Women taking hormone replacement therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal obesity | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Insulin Resistance | 6 Months |
Countries
Canada
Outcome results
None listed