Obesity
Conditions
Keywords
dairy products, calcium, fat excretion, energy excretion
Brief summary
The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.
Detailed description
Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles. The aim of this study is to examined if a high calcium intake from dairy products, in diets high or normal in fat content, have an effect on fecal energy and fat excretion, concentrations of substrates involved in energy metabolism and blood pressure.
Interventions
OTHERDairy calcium
Diets with different content of calcium and fat
Sponsors
Arla Foods
The Danish Dairy Research Foundation, Denmark
FOOD Graduate School, the Royal Veterinary & Agricultural University, Denmark
Danish Research Agency
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy meals * BMI 24-31 kg/m2 * age between 18-50 years
Exclusion criteria
* donation of blood 6 months before and under the study * milk allergy, diabetes, hypertension, hyperlipidemia, cronic infectious disease * use of dietary supplements 3 months before and under the study * smoking * elite athletes * use of medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal fat excretion, fecal energy excretion, calcium excretion, cholesterol | — |
Secondary
| Measure | Time frame |
|---|---|
| Vitamin D, changes in lipolyse | — |
Countries
Denmark
Contacts
Primary ContactArne Astrup, Prof. MD
Outcome results
None listed