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Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen

Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen After Low-Dosed Specific Bronchial Provocation

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00519740
Enrollment
120
Registered
2007-08-23
Start date
2006-08-31
Completion date
2008-12-31
Last updated
2009-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergy, Bronchial Asthma, Bronchial Hyperreactivity, Hypersensitivity

Keywords

grass-pollen, allergy, bronchial hyperreactivity, asthma

Brief summary

The study is meant to observe the influence of nutrition on nasal and bronchial discomfort in patients with allergy on grass pollen after specific bronchial provocation. Therefore, the investigators will record the patients' nutrition habits and measure the blood level of long chained polyunsaturated fatty-acids.

Interventions

OTHERinhalative specific bronchial provocation with grass-pollen

Sponsors

Johann Wolfgang Goethe University Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* age \>12 and \<45 years * informed consent * Known allergy on grass-pollen

Exclusion criteria

* age \<12 and \>45 years * Clinical asthma requiring regular inhalation * vital capacity \>80% * FEV1 \< 75% * Chronic disease * pregnancy * Inhalative or systemic steroid use * substance abuse * incapability of understanding the study's purpose and performance

Design outcomes

Primary

MeasureTime frame
correlation of the blood fatty-acid level and bronchial hyperreactivity, measured as the exhaled NO.aug 2006 - feb 2007

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 31, 2026