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Family Therapy for Adolescent Bulimia Nervosa

Family Therapy for Adolescent Bulimia Nervosa: A Controlled Comparison

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00518843
Enrollment
80
Registered
2007-08-21
Start date
2001-04-30
Completion date
2006-05-31
Last updated
2013-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bulimia Nervosa

Keywords

binge eating, purging

Brief summary

The primary hypotheses are: * A procedurally distinct family therapy is an effective and essential way to reduce bingeing and purging in adolescents with BN, and leads to the long-term amelioration of bulimic symptoms. * Family therapy is an effective way to bring about meaningful improvements in family interaction. * Family therapy will produce significantly larger reductions in bulimic symptoms and improved family interaction in adolescents with BN compared to a control supportive psychotherapy.

Detailed description

Bulimia nervosa (BN) is a disabling eating disorder and affects as many as 2% of young women. It is a major source of psychiatric and medical morbidity that often impairs several areas of functioning. Even more alarming is the fact that BN is occurring with increasing frequency among adolescents and preadolescents. Applying stringent diagnostic criteria for BN, studies have found 2-5% of adolescent girls surveyed qualify for diagnosis of BN. Research specific to treatment of child and adolescent eating disorders remains limited. No psychological treatment has been systematically evaluated in the treatment of adolescents with BN. However, a series of studies from the Maudsley Hospital in London have shown that family therapy (the 'Maudsley Approach') is effective in the treatment of adolescents with anorexia nervosa (AN). These studies have shown that involving the parents and siblings in treatment has beneficial effects on reversing the course of the eating disorder as well as improving family interaction. A preliminary report from the Maudsley group has also shown that the 'Maudsley Approach' may be helpful in the treatment of adolescents with BN. Because most young adolescents still live with their families of origin, this raises the interesting clinical question that adolescent BN patients can also be successfully treated with family therapy. The proposed study has two specific aims: 1. To adapt and pilot a recently developed family therapy manual for adolescent AN for use in the treatment of adolescent BN patients. 2. To compare the efficacy of this conceptually and procedurally distinct family therapy treatment with individual control psychotherapy. To achieve these aims, we propose a five-year controlled treatment study to be carried out at The University of Chicago. Eighty newly referred adolescent patients meeting DSM-IV diagnostic criteria for BN will be randomly allocated to one of two groups: 1) family therapy or 2) the individual supportive control treatment. All patients will receive the same medical evaluation and monitoring throughout the study period. Assessment of psychiatric and medical outcome measures will be carried out at the onset of treatment, during treatment, at the end of treatment, and again at one-year follow-up. The clinical outcome variables assessed will include the EDE, KSADS, RSE, and EE.

Interventions

BEHAVIORALFBT-BN

Mobilizing parents to curtail binge eating and purging

BEHAVIORALSPT

Supportive the individual patient to explore factors that might underlie the eating disorder

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
University of Chicago
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 19 Years
Healthy volunteers
No

Inclusion criteria

* DSM-IV criteria for bulimia nervosa or partial bulimia nervosa

Exclusion criteria

* psychotic illness acute suicidality medical illness that impacts weight pregnant

Design outcomes

Primary

MeasureTime frame
Binge eating and purging frequency measured by the Eating Disorder Examination28 days

Secondary

MeasureTime frame
EDE Subscales28 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026