Local Anesthetics After Total Knee Arthroplasty

Local Anesthetics After Total Knee Arthroplasty: Intra- vs. Extraarticular Administration? A Randomized, Double-Blind, Placebo-Controlled Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00518674

Enrollment

Registered

2007-08-21

Start date

2007-01-31

Completion date

2007-09-30

Last updated

2007-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

pain, local infiltration analgesia

Brief summary

The aim of this randomized, double-blind and placebo-controlled study is to evaluate the specific role of injection of local anesthetic into the intra- vs. extraarticular tissues after toal knee arthroplasty.

Interventions

PROCEDURElocal infiltration analgesia

local wound infiltration with 30 ml ropivacaine 0.2 % (60 mg)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Able to give informed oral and written consent to participate * Able to speak Danish

Exclusion criteria

* Treatment with opioids * Body Mass Index \> 40

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale pain score	—

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026