Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species

Risk Factors for Quinolone Resistance Among Extended-Spectrum Beta-Lactamase-Producing Klebsiella Species

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00518661

Enrollment

500

Registered

2007-08-21

Start date

2007-08-31

Completion date

2017-12-31

Last updated

2018-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ESBL, Infection, Klebsiella Species, Quinolone Resistance

Keywords

quinolone resistance, ESBL, Klebsiella species, Infection

Brief summary

Detailed description

This is a retrospective chart review. This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species. Additionally, the adequacy of empiric antibiotic therapy for Klebsiella bloodstream infections will be assessed. This research is (c) important because identification of risk factors may allow earlier initiation of appropriate therapy in patients infected with these bacteria. Additionally, we will identify whether horizontal spread is responsible for this increasing trend.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* must be quinolone resistant among ESBL producing klebsiella species

Exclusion criteria

* Those not meeting entry criteria

Countries

United States

Outcome results