Continuous Positive Airway Pressure in Sleep Apnea Syndrome: Effects on Metabolic Syndrome and Cardiac Damage

Effects of the Continuous Positive Airway Pressure Ventilation on the Prevalence of the Metabolic Syndrome and Cardiac Morpho-Functional Characteristics in Sleep Apnea Syndrome

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00517777

Enrollment

100

Registered

2007-08-17

Start date

2007-08-31

Completion date

2010-08-31

Last updated

2007-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Remodelling, Continuous Positive Airway Pressure Ventilation, Metabolic Syndrome, Sleep Apnea Syndrome

Keywords

sleep apnea syndrome, metabolic syndrome, cardiac remodelling, continuous positive airway pressure ventilation

Brief summary

To assess in moderate to severe Obstructive Sleep Apnea the effects of one year therapy with nighttime continuous positive airway pressure ventilation on the prevalence of metabolic syndrome and cardiovascular damage.

Interventions

DEVICEcontinuous positive airway pressure ventilation

nighttime

BEHAVIORALdietary and life style recommendations

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

25 Years to 70 Years

Healthy volunteers

Inclusion criteria

* moderate to severe sleep apnea syndrome

Exclusion criteria

* cardiovascular diseases (coronary artery disease, stroke, peripheral artery disease) * thyroid diseases * diabetes

Design outcomes

Primary

Measure	Time frame
metabolic syndrome	one year
left ventricular mass	one year
diastolic function	one year

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026