Keratitis
Conditions
Keywords
keratopathy, exposure, intensive care, eye, ulcer, Corneal
Brief summary
Corneal damage in critically ill patients is common. There are currently two popular methods of treatment in the UK; hydrogel dressings and lubricating ointment. We propose to randomise patients to have a different treatment for each eye and see which one is more effective.
Detailed description
Microbial keratitis, particularly pseudomonas-related, has been widely reported amongst Intensive therapy unit (ITU) patients and the need for effective eye care in ITU has been recognised for some time. We compare two popular methods of eye care; a hydrogel dressing and lacrilube ointment. Each recruited patient had each eye randomised to different treatments. Daily ophthalmology ward rounds were undertaken to identify any corneal exposure keratopathy. Patients were removed from the trial if one eye developed significant exposure needing treatment.
Interventions
OTHERHydrogel dressing
3x3cm hydrogel dressing over closed eye
OTHERLacrilube ointment
lubricant put into eye (inferior formix)
Sponsors
Barts & The London NHS Trust
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients admitted to Intensive care and expected to stay for more than 2 days
Exclusion criteria
* Primary orbital injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development of clinically significant corneal exposure | throughout length of admission to ITU |
Outcome results
None listed