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Implementation of a Pharmacy-Intervention to Enhance Prescription and Use of Lipid-Lowering Drugs

Implementation of a Pharmacy-Intervention to Enhance Prescription and Use of Lipid-Lowering Drugs. A Randomized Trial.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00509717
Enrollment
70
Registered
2007-07-31
Start date
2006-10-31
Completion date
2008-03-31
Last updated
2008-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases

Keywords

quality of health care, prescriptions, drug, anticholesteremic agents, community pharmacy services

Brief summary

The purpose of this study is to determine the effectiveness of maximal support of community pharmacies to implement a pharmaceutical care model for improving underprescription and treatment persistence regarding lipid-lowering medication in patients with cardiovascular disease.

Detailed description

Cardiovascular disease is the main cause of death in large parts of the world. Next to life style changes, pharmaceutical treatment is a keystone in the treatment of cardiovascular disease. Despite the strong evidence for the effectiveness of lipid-lowering therapy, less than half of the people eligible are treated. With specific medication searches in the community pharmacy database, an easy tool for detecting patients who are undertreated is available. Based on this tool, a pharmaceutical care model for improving underprescription and treatment persistence regarding lipid-lowering medication in patients with cardiovascular disease was constructed. Moreover, it is not known yet how to implement this pharmaceutical care model in community pharmacies effectively. With multifaceted interventions the behaviour of health professionals can be changed. In this study the effectiveness of a maximal support strategy, including interactive educational meetings, reminders, audit and feedback, is compared to a minimal implementation strategy.

Interventions

OTHERintensive implementation programme

educational manual; interactive educational meeting tailored to individual needs; reminders and feedback by 3 newsletters and at least 3 telephone calls.

OTHERcontrol

educational manual

Sponsors

Zorgverzekeraar CZ
CollaboratorOTHER
Scientific Institute for Dutch Pharmacists, The Netherlands
CollaboratorOTHER
Radboud University Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* pharmacies: resident in the south of the Netherlands * patients: with antiplatelet therapy and without lipid-lowering medication

Exclusion criteria

for patients: * terminal disease * severe mental disorder

Design outcomes

Primary

MeasureTime frame
The percentage of selected (=undertreated) patients receiving at least one prescription for lipid-lowering medication.six months after the general practitioner received the list with selected patients

Secondary

MeasureTime frame
Differences in prescribing for age categories and co-medication.six months

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 27, 2026